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In AD there is a decreased metabolism of the parietal lobes (yellow arrows), whereas in FTD, there is frontal hypometablism (red arrows). Alzheimers Disease. Study the image, then continue reading. Presenile AD with normal hippocampus and severe parietal atrophy. Mild cognitive impairment is a relatively recent term used to describe people who have some problems with their memory, but do not actually have dementia, since dementia is defined as having problems in two or more cognitive domains. Some of these patients will be in the early stages of Alzheimer's disease or another dementia, so it is important to identify them. Finding MTA is a strong risk-factor for progression to dementia. The images show a patient with a strategic PCA infarction involving the hippocampus. This type of infarct can result in sudden dementia if located in the dominant hemisphere. It will usually not result in dementia if it occurs in the non-dominant hemisphere. Cognitive dysfunction in VaD can be the result of (2): The problem however is, that white matter hyperintensities and lacunes are also frequently observed in non-demented elderly and at some level can be regarded as normal findings in aging. To overcome this problem the NINDS-AIREN International Work Group has formulated criteria for the history and physical, radiological, (see above) and pathological examination to classify patients as having possible, probable and definite VaD. However considerable interobserver variability exists for the assessment of the radiological part of these NINDS-AIREN criteria and some level of training is mandatory (2).
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